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Can Hormone Imbalances Cause Inflammation?

Taryn Mattern

Can Hormone Imbalances Cause Inflammation?

Ladies, have you ever wondered, “Can hormone imbalances cause inflammation?,” “Could this be why I’m struggling with persistent fatigue, joint pain, skin problems or digestive issues, even unexplained weight gain?” 


It's not just a general feeling of being 'off,' these symptoms disrupt your daily life. Well…these common, nagging symptoms could be manifesting from underlying hormonal imbalances and inflammation! 


Understanding Hormonal Imbalances

When it comes to your health, hormones play a huge part in how you feel. They act like messengers, controlling everything from growth and metabolism to your mood and reproductive system. But, if the levels of these hormones in your blood are off, even a little, it can cause symptoms like fatigue, mood swings, or issues with your metabolism.


Your hormones are kept in check by glands known as the endocrine system. This includes glands like your adrenal glands, parathyroid, pituitary gland, and thyroid. They produce, store, and release specific hormones into your blood. These hormones then travel to different parts of your body to do their job and allow your body to communicate. 


When hormones become imbalanced, it can trigger inflammation in the body. Hormones like cortisol, insulin, and estrogen play critical roles in regulating inflammation. An imbalance in these hormones can lead to increased inflammatory responses, contributing to various health issues such as joint pain, digestive problems, and chronic diseases. Addressing hormone imbalances is essential to managing and reducing inflammation, thereby supporting overall health and well-being.


What is the Big Deal With Inflammation?

Inflammation isn’t always a bad thing. Inflammation is your body's natural defense mechanism against injuries, infections, and toxins. But when it gets out of hand, and becomes chronic, it's like a constant alarm going off in your body, leading to chronic pain, fatigue, skin issues, and a host of other problems that can seriously mess with your daily life and overall well being.Chronic inflammation can be due from stress, underlying infections, nutrient deficiencies, gut imbalances and what I commonly see with my clients is hormone imbalances. 


But what most women don’t understand is that chronic inflammation is like a ticking time bomb for serious diseases. It can quietly contribute to heart disease, cancer, and even Alzheimer's disease down the line. And the worst part? You might not even realize it's happening until it's too late. 


Inflammation can be a silent disruptor that can significantly impact your health, well-being, and even your happiness. It can make your life uncomfortable, cause persistent health issues, and potentially set the stage for serious diseases. That's why it's crucial to pay attention to it, take it seriously, and take steps to control it.


Can Hormone Imbalances Cause Inflammation? 

Yes, hormonal imbalances can lead to chronic inflammation, and unfortunately is very common among women. Here’s how…


Cortisol and Inflammation

Let's take cortisol, for example. Your adrenal glands, located right on top of your kidneys, produce this hormone. It has a direct and substantial effect on your body's inflammatory response. When your glands produce either too much or too little cortisol, it can cause your immune system to become overactive. This overactivity can lead to uncontrolled inflammation, which can harm your overall health.


Signs of a Cortisol Imbalance

  • Constantly feeling tired, despite getting a full night's sleep

  • Struggling to concentrate at work, with a mind that feels foggy

  • Dealing with mood swings that seem to affect relationships and daily life

  • Noticing unexplained weight gain, especially around the belly, despite maintaining a usual diet and exercise routine

  • Finding out blood pressure is high, which seems unusual for someone in their 30s

  • Always feeling thirsty and making frequent trips to the bathroom


Estrogen and Inflammation

Now, let's talk about sex hormones, like estrogen and progesterone. These hormones don't work alone...they interact actively with your immune cells and play a crucial role in regulating your immune response. If the levels of these hormones aren't balanced - if they're either too high or too low - it can lead to chronic inflammation.


Estrogen plays a dual role when it comes to inflammation. At the right levels, it helps regulate your immune response and has anti-inflammatory effects, keeping chronic inflammation at bay. But when estrogen levels are too high, which can happen with estrogen dominance, it can ramp up inflammation. This might show up as joint pain, swelling, or even an increased risk of autoimmune diseases.


On the other side, low estrogen levels can also be a problem. While this is more common during menopause, it can happen at other times too. When estrogen dips, its anti-inflammatory effects weaken, making your body more prone to inflammation. This could mean more joint pain and stiffness, among other symptoms.


Progesterone is another key player in this balance. It generally helps to counteract the pro-inflammatory effects of estrogen. However, when progesterone is low – as it can be with conditions like PCOS or during perimenopause – the imbalance can tip toward more inflammation.


This delicate balance between estrogen, progesterone, and your immune system is crucial. When these hormones are out of sync, your immune system can go haywire, leading to chronic inflammation and a host of related issues like increased pain, autoimmune disorders, and metabolic problems.


Signs of an Estrogen Imbalance

  • Increased PMS or menopausal symptoms

  • Irregular periods

  • Bloating

  • Breast swelling and tenderness

  • Mood swings

  • Hair loss

  • Cold hands or feet

  • Fatigue

  • Difficulty sleeping

  • Memory problems


Thyroid Imbalances and Inflammation 

Thyroid imbalances, such as hypothyroidism or hyperthyroidism, can significantly affect inflammatory processes in the body. The thyroid gland releases hormones that regulate metabolism, and imbalances can disrupt this balance. In hypothyroidism and hyperthyroidism,  chronic inflammation could be an issue.


Your thyroid gland releases hormones like thyroxine (T4) and triiodothyronine (T3), which are essential for regulating your metabolism. When these hormones are out of balance, it can disrupt the delicate equilibrium of your body's functions.


In hypothyroidism, where the thyroid produces too little hormone, your metabolism slows down. This can lead to a buildup of inflammatory substances in your body, causing chronic inflammation. You might experience symptoms like fatigue, weight gain, joint pain, and muscle aches. The sluggish metabolism can also make it harder for your body to eliminate toxins, further contributing to inflammation.


Hyperthyroidism, on the other hand, is when the thyroid produces too much hormone, speeding up your metabolism. This overactivity can also lead to chronic inflammation. Symptoms might include weight loss, anxiety, rapid heartbeat, and muscle weakness. The constant high metabolic rate can put stress on your body, causing it to produce more inflammatory cytokines and leading to conditions like Graves' disease.


Signs of an Thyroid imbalance

  • Unexplained weight gain or difficulty losing weight

  • Constant fatigue, even after a good night's sleep

  • Feeling cold, even in warm temperatures

  • Hair loss or thinning hair

  • Dry, rough skin

  • Irregular or heavy menstrual periods

  • Difficulty concentrating or 'brain fog'

  • Changes in mood, such as increased anxiety or feelings of depression


So, understanding the relationship between hormonal imbalance and inflammation is absolutely essential. It might take years, even decades, for the symptoms and health complications of chronic inflammation to show up. But remember, it's never too late to start learning and taking care of your body.


How to Balance Hormones and Reduce Inflammation

So, how can you balance hormones and reduce inflammation?

  • Diet: Prioritize foods that are known to help balance hormones. However, remember that everyone’s body is different, and a personalized diet tailored to your unique needs can make a significant impact (this is where the benefits of functional lab testing come in!). Here are some hormone-balancing foods to consider:These include:

    • Flaxseeds: Flaxseeds are rich in lignans, compounds that help balance estrogen levels in the body. You can add them to your smoothies, cereals, or salads.

    • Broccoli/ Cauliflower: This vegetable is rich in compounds that help the liver metabolize estrogen. It can be enjoyed steamed, roasted, or even raw in salads.

    • Pomegranate: This fruit has anti-inflammatory properties and may help lower levels of the stress hormone cortisol. Try adding it to your salads or enjoy it as a juice.

  • Exercise: Regular physical activity can help balance your hormones and reduce inflammation. It doesn't have to be intense - even a daily walk can make a difference.

  • Sleep: Prioritize getting 7-9 hours of sleep per night. Lack of sleep can disrupt your hormones, leading to imbalances.

  • Stress management: Techniques like mindfulness and yoga can help reduce stress levels, which in turn can help balance hormones. Set aside time each day for these activities.

  • Start small: If these changes feel overwhelming, remember to start small. Even a single step towards improving your diet, sleep, exercise, or stress management habits can make a significant difference in your hormonal health.

  • Get functional hormone testing done: This comprehensive test that I run for my clients gives us detailed insights into what specific hormones need support. From there, I can recommend specific foods, supplements and even lifestyle behaviors that are going to be the most effective in getting your hormone levels back into balance as well as strategies to tackle the inflammation head on. 


Want to get to the root of your underlying hormone imbalances and inflammation? Book a call to get started!

If you are struggling with these issues, apply for my 1:1 Functional Nutrition coaching! I’m Taryn Mattern, a functional & holistic nutritionist for women. I’ve helped hundreds of women overcome their annoying and even painful symptoms by providing personalized advice on diet and lifestyle changes to help balance their hormones and reduce inflammation.


Remember, the connection between hormonal imbalances and inflammation is real. By taking a holistic approach to your health, you can manage your hormones, reduce inflammation, and feel better than ever.


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